When a cancer, or any patient doesnt want to take painkillers that cause constipation.
When a patient wants natural pain relief that does not involve physical addiction/dependence.
When someone with depression doesnt want to take drugs that list suicide as a side effect.
When a joint of low grade does more for pain relief than 60mg morphine.
When it clears up speech impediments instantly, when no recommended pharmaceutical will.
I could do this all day, but im just listing the ones off the top of my head that ive seen with my own eyes most recently.